fenugreek

Botanical name
Trigonella foenum-graecum
Parts used and where grownAlthough originally from southeastern Europe and western Asia, fenugreek grows today in many parts of the world, including India, northern Africa, and the United States. The seeds of fenugreek are used medicinally.
Fenugreek has been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings - Health Concerns*** - High cholesterol
*** - Type 2 diabetes
** - Atherosclerosis
** - High triglycerides
* - Constipation
* - Type 1 diabetes
*** - Reliable and relatively consistent scientific data showing a substantial health benefit.
** - Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
* - For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.
Historical or traditional use (may or may not be supported by scientific studies)
A wide range of uses were found for fenugreek in ancient times. Medicinally it was used for the treatment of
wounds, abscesses, arthritis, bronchitis, and digestive problems. Traditional Chinese herbalists used it for kidney problems and conditions affecting the male reproductive tract.1 Fenugreek was, and remains, a food and a spice commonly eaten in many parts of the world.
Active constituentsFenugreek seeds contain alkaloids (mainly trigonelline) and protein high in lysine and L-tryptophan. Its steroidal saponins (diosgenin, yamogenin, tigogenin, and neotigogenin) and mucilaginous fiber are thought to account for many of the beneficial effects of fenugreek. The steroidal saponins are thought to inhibit cholesterol absorption and synthesis,2 while the fiber may help lower blood sugar levels.3 One human study found that fenugreek can help lower cholesterol and blood sugar levels in people with moderate atherosclerosis and non-insulin-dependent (type 2) diabetes.4 Preliminary and double-blind trials have found that fenugreek helps improve blood sugar control in patients with insulin-dependent (type 1) and non-insulin-dependent (type 2) diabetes.5 6 7 Double-blind trials have shown that fenugreek lowers elevated cholesterol and triglyceride levels in the blood,8 9 This has also been found in a controlled clinical trial with diabetic patients with elevated cholesterol.10 Generally, fenugreek does not lower HDL (“good”) cholesterol levels.
How much is usually taken?
Due to the somewhat bitter taste of fenugreek seeds, de-bitterized seeds or encapsulated products are preferred. The German Commission E monograph recommends a daily intake of 6 grams.11 The typical range of intake for
diabetes or cholesterol-lowering is 5–30 grams with each meal or 15–90 grams all at once with one meal. As a tincture, 3–4 ml of fenugreek can be taken up to three times per day.
Are there any side effects or interactions?
Use of more than 100 grams of fenugreek seeds daily can cause intestinal upset and nausea. Otherwise, fenugreek is extremely safe. Due to the potential uterine stimulating properties of fenugreek, which may cause miscarriages, fenugreek should not be used during
pregnancy.12
Drug InteractionsCertain medicines interact with fenugreek: Some interactions may increase the need for fenugreek (+), other interactions may be negative (-) and indicate fenugreek should not be taken without first speaking with your physician or pharmacist, others may require further explanation (?). Refer to the individual drug article for specific details about an interaction.
Note: The following list only includes the generic or class name of a medicine. To find a specific brand name, use the
Medicines index.Glipizide (-)Heparin (-)Insulin (+)Ticlopidine (-)Warfarin (-)